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Article

Mapping EBNA-1 Domains Involved in Binding to Metaphase Chromosomes

1 May 1999

Abstract excerpt

The Epstein-Barr virus (EBV) genome can persist in dividing human B cells as multicopy circular episomes. Viral episomes replicate in synchrony with host cell DNA and are maintained at a relatively constant copy number for a long time. Only two viral elements, the replication origin OriP and the EBNA-1 protein, are required for the persistence of viral genomes during latency. EBNA-1 activates OriP during the S...

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PMID: 10196336
DOI: 10.1128/jvi.73.5.4385-4392.1999

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Mapping EBNA-1 Domains Involved in Binding to Metaphase ChromosomesPMID 10196336Read ↗

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The Epstein-Barr Virus Episome Maneuvers between Nuclear Chromatin Compartments during ReactivationSemantic proximity Read ↗

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