Article
Two common SNPs in pri-miR-125a alter the mature miRNA expression and associate with recurrent pregnancy loss in a Han-Chinese population.
RNA biology - 1 Jan 2000
Hu Yi, Liu Chun-Mei, Qi Lu, He Tian-Zhu, Shi-Guo Liu, Hao Chan-Juan, Cui Yi, Zhang Ning, Xia Hong-Fei, Ma Xu
Abstract excerpt
Although there are plenty of evidence that single-nucleotide polymorphisms (SNPs) that fall within coding sequences of genes are involved in recurrent pregnancy loss (RPL), it is still unknown whether the polymorphisms in microRNAs (miRNAs) are related with RPL. In this study, we established this kind of association by confirming significant differences in genotype distribution of rs41275794 (P= 0.0005) and...
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