Article
Heme oxygenase-1 gene promoter polymorphism and restenosis following coronary stenting.
European heart journal - 1 Apr 2007
Tiroch Klaus, Koch Werner, von Beckerath Nikolas, Kastrati Adnan, Schömig Albert
Abstract excerpt
AIMS: Gene expression analyses, cell culture experiments, animal models, and association studies suggest a protective role of the heme oxygenase-1 (HO-1) protein against restenosis. The length of a polymorphic (GT)n dinucleotid repeats sequence in the HO-1 gene promoter influences the transcriptional activity. We evaluated, whether an association existed between this polymorphism and the incidence of restenosis...
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