Article
Clinical restenosis after coronary stent implantation is associated with the heme oxygenase-1 gene promoter polymorphism and the heme oxygenase-1 +99G/C variant.
Clinical chemistry - 1 Sept 2005
Gulesserian Talin, Wenzel Catharina, Endler Georg, Sunder-Plassmann Raute, Marsik Claudia, Mannhalter Christine, Iordanova Nelly, Gyöngyösi Mariann, Wojta Johann, Mustafa Stefan, Wagner Oswald, Huber Kurt
Abstract excerpt
BACKGROUND: Vascular remodeling after percutaneous coronary stent implantation frequently leads to restenosis. Heme oxygenase 1 (HO-1) is involved in the generation of the endogenous antioxidant bilirubin and carbon monoxide, both of which exert antiinflammatory and antiproliferative effects. The aim of the present study was to evaluate the influence of genetic risk factors combined with the conventional risk...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.