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Article

Cyclin D1 gene G870A polymorphism predicts response to neoadjuvant radiotherapy and prognosis in rectal cancer.

International journal of radiation oncology, biology, physics - 15 Jul 2007

Ho-Pun-Cheung Alexandre, Assenat Eric, Thezenas Simon, Bibeau Frédéric, Rouanet Philippe, Azria David, Cellier Dominic, Grenier Jean, Ychou Marc, Senesse Pierre, Lopez-Crapez Evelyne

Abstract excerpt

PURPOSE: To investigate whether CCND1 genetic variations associated with a constitutive nuclear protein may influence either the pathologic response to preoperative RT or the prognosis in a series of rectal cancer patients. METHODS AND MATERIALS: Seventy rectal cancer patients treated by neoadjuvant radiotherapy were included in the study. CCND1 exon 5 mutations were screened, and the G870A polymorphism was...

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Source

Identifiers

PMID: 17398034
DOI: 10.1016/j.ijrobp.2007.01.022

Genes

CCND1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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