Article
Interleukin-18 gene polymorphism, but not interleukin-2 gene polymorphism, is associated with rheumatoid arthritis.
Immunogenetics - 1 Jun 2007
Lee Cheng-Chun, Lin Wei-Yong, Wan Lei, Tsai Yuhsin, Lin Ying-Ju, Tsai Chang-Hai, Huang Chung-Ming, Tsai Fuu-Jen
Abstract excerpt
To investigate whether polymorphisms of IL-2 and IL-18 genes are associated with rheumatoid arthritis (RA), polymorphisms of IL-2 and IL-18 genes were detected by polymerase-chain-reaction-based restriction analysis in the patients with RA and normal controls. The results for the IL-18 gene revealed a significant difference between the patients and the normal controls (p = 0.000003), but there was no significant...
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