Article
Phenotype-directed analysis of genotype in early-onset, familial breast cancers.
Pathology - 1 Dec 2006
Price Gareth R, Armes Jane E, Ramus Susan J, Provenzano Elena, Kumar Beena, Cowie Tiffany F, Ciciulla John, Hutchins Anne-Marie, Thomas Mervyn, Venter Deon J
Abstract excerpt
UNLABELLED: Considerable heterogeneity of morphology and disease outcome exists within breast cancers (BC), which likely reflects variable molecular pathogeneses within this broad clinical group. AIM: To evaluate the underlying genomic alterations associated with familial, early-onset BC (EOBC) phenotypes, in order to improve the management of this disease. METHODS: Using hierarchical clustering of morphological...
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