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Article

Use of pyrosequencing to identify point mutations in domain V of 23S rRNA genes of linezolid-resistant Staphylococcus aureus and Staphylococcus epidermidis.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 1 Mar 2007

Zhu W, Tenover F C, Limor J, Lonsway D, Prince D, Dunne W M, Patel J B

Abstract excerpt

A pyrosequencing assay was used for the rapid characterization of linezolid-resistant isolates of Staphylococcus aureus and Staphylococcus epidermidis. The assay identified base substitutions in copies of the 23S rRNA gene and determined the percentage of alleles with the mutation. Modifications of the assay were necessary to identify all mutations in the 23S rRNA genes of S. epidermidis that were associated with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 17393201
DOI: 10.1007/s10096-007-0261-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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