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Article

Molecular characterisation of linezolid resistance in two vancomycin-resistant (VanB) Enterococcus faecium isolates using Pyrosequencing.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 1 Sept 2008

Saager B, Rohde H, Timmerbeil B S, Franke G, Pothmann W, Dahlke J, Scherpe S, Sobottka I, Heisig P, Horstkotte M A

Abstract excerpt

In this paper, we describe the phenotypic and molecular characteristics of two clinically relevant, vancomycin-resistant (VanB), linezolid-resistant Enterococcus faecium isolates. Pyrosequencing showed the G to T single nucleotide polymorphism at bp 2576 in the genes coding for 23S rRNA and was used to quantify the proportion of G to T mutations among six different 23S rRNA genes in E. faecium as a marker for the...

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PMID: 18421487
DOI: 10.1007/s10096-008-0514-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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