Article
ACP1 and Th class of immunological disease: evidence of interaction with gender.
International archives of allergy and immunology - 1 Jan 2007
Gloria-Bottini F, Bottini N, Renzetti G, Bottini E
Abstract excerpt
BACKGROUND: Data collected by our group in the past years indicate a relationship between ACP1 genetic polymorphism and susceptibility/resistance to immunological diseases. Recent observations suggest that through modulation of ZAP-70 activity, the enzyme may influence T cell activation. In view of the current interest in gender differences in autoimmune diseases we reviewed our data to enlighten possible effects...
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