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Article

Sporadic and Lynch syndrome-associated mismatch repair-deficient brain tumors.

Laboratory investigation; a journal of technical methods and pathology - 1 Feb 2022

Kim Hyunhee, Lim Ka Young, Park Jin Woo, Kang Jeongwan, Won Jae Kyung, Lee Kwanghoon, Shim Yumi, Park Chul-Kee, Kim Seung-Ki, Choi Seung-Hong, Kim Tae Min, Yun Hongseok, Park Sung-Hye

Abstract excerpt

Mismatch repair-deficient (MMRD) brain tumors are rare among primary brain tumors and can be induced by germline or sporadic mutations. Here, we report 13 MMRD-associated (9 sporadic and 4 Lynch syndrome) primary brain tumors to determine clinicopathological and molecular characteristics and biological behavior. Our 13 MMRD brain tumors included glioblastoma (GBM) IDH-wildtype (n = 9) including 1 gliosarcoma,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34848827
DOI: 10.1038/s41374-021-00694-3
PMCID: PMC8784316

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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