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Article

Association study of cholesterol-related genes in Alzheimer's disease.

Neurogenetics - 1 Aug 2007

Wollmer M Axel, Sleegers Kristel, Ingelsson Martin, Zekanowski Cezary, Brouwers Nathalie, Maruszak Aleksandra, Brunner Fabienne, Huynh Kim-Dung, Kilander Lena, Brundin Rose-Marie, Hedlund Marie, Giedraitis Vilmantas, Glaser Anna, Engelborghs Sebastiaan, De Deyn Peter P, Kapaki Elisabeth, Tsolaki Magdalini, Daniilidou Makrina, Molyva Dimitra, Paraskevas George P, Thal Dietmar R, Barcikowska Maria, Kuznicki Jacek, Lannfelt Lars, Van Broeckhoven Christine, Nitsch Roger M, Hock Christoph, Papassotiropoulos Andreas

Abstract excerpt

Alzheimer's disease (AD) is a genetically complex disorder, and several genes related to cholesterol metabolism have been reported to contribute to AD risk. To identify further AD susceptibility genes, we have screened genes that map to chromosomal regions with high logarithm of the odds scores for AD in full genome scans and are related to cholesterol metabolism. In a European screening sample of 115 sporadic AD...

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Source

Identifiers

PMID: 17387528
DOI: 10.1007/s10048-007-0087-z

Genes

HMGCS2
ABCG1
FDPS
NPC2
ACAD8
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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