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Article

Sinomenine inhibits maturation of monocyte-derived dendritic cells through blocking activation of NF-kappa B.

International immunopharmacology - 1 May 2007

Zhao Yi, Li Juan, Yu Keqiang, Liu Yi, Chen Xiaoguang

Abstract excerpt

Sinomenine, a purified alkaloid extracted from Sinomenium acutum, has been employed to treat arthritis for a long time. Previous studies have shown that sinomenine has favorable function of immunosuppression, but the exact mechanism has not been illustrated yet. In this study, we investigated the effect of sinomenine on human monocyte-derived dendritic cells (DCs). Lipopolysaccharide (LPS) induced DCs, exposed to...

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Share to Anti-Inflammatory Agents, Non-Steroidal
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17386411
DOI: 10.1016/j.intimp.2007.01.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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