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Article

Sinulariolide suppresses LPS‑induced phenotypic and functional maturation of dendritic cells.

Molecular medicine reports - 1 Nov 2017

Chung Ting-Wen, Li Yi-Rong, Huang Wei Yuan, Su Jui-Hsin, Chan Hong-Lin, Lin Sheng-Hao, Liu Chin-San, Lin Shih-Chao, Lin Chi-Chien, Lin Ching-Hsiung

Abstract excerpt

The dendritic cell (DC) maturation process is essential for the development of T cell responses and immune tolerance. Accordingly, DCs are considered a major target in the development of immunomodulating agents. In the present study, the effect of sinulariolide, an active compound isolated from the cultured soft coral Sinularia flexibilis, on lipopolysaccharide (LPS)‑induced murine bone marrow‑derived DCs was...

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PMID: 28901434
DOI: 10.3892/mmr.2017.7480

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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