Article
A statistical model for assessing genetic susceptibility as a risk factor in multifactorial diseases: lessons from occupational asthma.
Environmental health perspectives - 1 Feb 2007
Demchuk Eugene, Yucesoy Berran, Johnson Victor J, Andrew Michael, Weston Ainsley, Germolec Dori R, De Rosa Christopher T, Luster Michael I
Abstract excerpt
BACKGROUND: Incorporating the influence of genetic variation in the risk assessment process is often considered, but no generalized approach exists. Many common human diseases such as asthma, cancer, and cardiovascular disease are complex in nature, as they are influenced variably by environmental, physiologic, and genetic factors. The genetic components most responsible for differences in individual disease risk...
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