Article
Pivotal role of the mineralocorticoid receptor in corticosteroid-induced adipogenesis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Jul 2007
Caprio Massimiliano, Fève Bruno, Claës Aurélie, Viengchareun Say, Lombès Marc, Zennaro Maria-Christina
Abstract excerpt
In addition to their role in controlling water and salt homeostasis, recent work suggests that aldosterone and mineralocorticoid receptors (MR) may be involved in adipocyte biology. This is of particular relevance given the role of MR as a high-affinity receptor for both mineralocorticoids and glucocorticoids. We have thus examined the effect of aldosterone and MR on white adipose cell differentiation. When cells...
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