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Article

T‐cell epitope mapping of ORF2 and ORF3 proteins of human hepatitis E virus

2 Aug 2006

Abstract excerpt

Little data are available on cellular immune responses during infection with hepatitis E virus (HEV). We therefore mapped CD4 T-cell epitopes in open reading frame (ORF)2 and ORF3 proteins of HEV using lymphocyte proliferation assays and overlapping peptide libraries. Proliferation of peripheral blood mononuclear cells from 40 patients with acute hepatitis E and 21 healthy controls with recombinant HEV ORF2...

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PMID: 17381721
DOI: 10.1111/j.1365-2893.2006.00796.x

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