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Comparative proteomic analysis associated with term placental insufficiency in cloned pig

23 Mar 2007

Abstract excerpt

Somatic cell-derived nuclear transfer (scNT) is a method of animal cloning in which the oocyte reprograms a somatic cell nucleus to divide and execute developmental programs. Despite many successes in this field, cloning by scNT remains very inefficient. Unlike other cloned animals, pigs derived by scNT have placentas with severe villous hypoplasia. To obtain a better understanding of the protein networks...

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PMID: 17380531
DOI: 10.1002/pmic.200601045

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