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Article

Telling Cells How to Die: Docetaxel Therapy in Cancer Cell Lines

1 Apr 2007

Abstract excerpt

Taxanes (paclitaxel and docetaxel) are antimicrotubule agents used in the clinical practice for the treatment of solid tumors. The molecular mechanisms of taxane-dependent cytotoxicity are only partially known. In vitro, different modes of action have been established for paclitaxel according to its concentration. A similar phenomenon has been shown for other microtubule-stabilizing drugs, including docetaxel....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 17377494
DOI: 10.4161/cc.6.7.4050

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