Article
Breast cancer cells respond differently to docetaxel depending on their phenotype and on survivin upregulation.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Feb 2016
De Iuliis Francesca, Salerno Gerardo, Giuffrida Anna, Milana Bernardina, Taglieri Ludovica, Rubinacci Giovanna, Giantulli Sabrina, Terella Federica, Silvestri Ida, Scarpa Susanna
Abstract excerpt
Breast cancer is characterized by molecular heterogeneity, and four major breast cancer subtypes have been identified, each characterized by significant differences in survival, prognosis, and response to therapy. We have studied the effects of docetaxel treatment on apoptosis and survivin expression in four breast cancer cell lines: MCF7 (luminal A: estrogen receptor-positive and progesterone receptor-positive,...
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