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Host Transcription Profiles upon Primary Respiratory Syncytial Virus Infection

22 Mar 2007

Abstract excerpt

Respiratory syncytial virus (RSV) is a common cause of severe lower respiratory tract infection in children. Severe RSV disease is related to an inappropriate immune response to RSV resulting in enhanced lung pathology which is influenced by host genetic factors. To gain insight into the early pathways of the pathogenesis of and immune response to RSV infection, we determined the transcription profiles of lungs...

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PMID: 17376894
DOI: 10.1128/jvi.02220-06

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