Article
TSLP-Driven Chromatin Remodeling and Trained Systemic Immunity after Neonatal Respiratory Viral Infection
29 Jan 2021
Abstract excerpt
Abstract Our studies have previously shown a role for persistent TSLP production in the lungs of mice after early-life respiratory syncytial virus (RSV) infection that leads to an altered immune phenotype, including accumulation of “inflammatory” dendritic cells (DC). This study investigates the role of TSLP driving systemic trained immunity in DC in early-life RSV-infected mice. Bone marrow–derived DCs (BMDC)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
