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Article

Effect of MDR1 gene polymorphism on progression of end-stage renal disease.

Acta pharmacologica Sinica - 1 Apr 2007

Zhang Wei-xia, Chen Bing, Zhang Wen, Chen Nan, Yu Zi-cheng, Cai Wei-min

Abstract excerpt

AIM: P-glycoprotein is localized at the apical brush-border membrane of the proximal renal tubule and functions as extruding toxins and xenobiotics out of cells. The difference of P-glycoproteinos function resulted from single nucleotide polymorphisms in MDR1 (multidrug resistance gene encoding f...

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Identifiers

PMID: 17376299
DOI: 10.1111/j.1745-7254.2007.00517.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17376299-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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