Article
Analysis of common transforming growth factor beta-1 gene polymorphisms in gastric and duodenal ulcer disease: pilot study.
Journal of gastroenterology and hepatology - 1 Apr 2007
Polonikov Alexey V, Ivanov Vladimir P, Belugin Dmitry A, Khoroshaya Irina V, Kolchanova Inessa O, Solodilova Mariya A, Tutochkina Margarita P, Stepchenko Alexander A
Abstract excerpt
BACKGROUND AND AIM: Transforming growth factor-beta1 (TGF-beta1) has been shown to be an important cytokine that plays a role in cell proliferation, differentiation, tissue injury repair and ulcer healing. The purpose of this pilot study was to investigate if common polymorphisms Leu10Pro, Arg25Pro and C-509T within the TGF-beta1 gene are associated with susceptibility to gastric and duodenal ulcer disease in...
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