Article
FOXA1: Growth inhibitor and a favorable prognostic factor in human breast cancer
12 Dec 2006
Abstract excerpt
The transcription factor Forkhead-box A1 (Foxa1), a member of the FOX class of transcription factors, has been implicated in the pathogenesis of lung, esophageal and prostate cancers. We have recently identified transcriptional activation of p27 by FOXA1. In this study, we analyzed the activities and expression pattern of FOXA1 in breast cancer. Forced expression of FOXA1 inhibited clonal growth of breast cancer...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
