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Article

Tissue-driven hypothesis with Gene Ontology (GO) analysis.

Annals of biomedical engineering - 1 Jun 2007

Su Zhixi, Huang Yong, Gu Xun

Abstract excerpt

Most of the genes are under selective pressure to maintain their expression levels in the tissues. In a recent study, we have proposed a "tissue-driven" hypothesis stating that the stabilizing constraints on gene expression levels can be partitioned among tissues; tissues differ in their tolerance to gene expression variances; and the constraints on expression divergence is correlated with the constraints on...

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PMID: 17372837
DOI: 10.1007/s10439-007-9269-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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