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Article

Insulin growth factor-binding protein 2 is a candidate biomarker for PTEN status and PI3K/Akt pathway activation in glioblastoma and prostate cancer

19 Mar 2007

Abstract excerpt

PTEN is an important tumor-suppressor gene associated with many cancers. Through expression profiling of glioblastoma tissue samples and prostate cancer xenografts, we identified a molecular signature for loss of the PTEN tumor suppressor in glioblastoma and prostate tumors. The PTEN signature consists of a minimum of nine genes, several of which are involved in various pathways already implicated in tumor...

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Share to Growth Hormone and Insulin-like Growth Factors
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 17372210
DOI: 10.1073/pnas.0609139104

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