Article
Farnesyl diphosphate synthase: a novel genotype association with bone mineral density in elderly women.
Maturitas - 20 Jul 2007
Levy Matthew E, Parker Robert A, Ferrell Robert E, Zmuda Joseph M, Greenspan Susan L
Abstract excerpt
OBJECTIVE: We evaluated the association between a single nucleotide polymorphism in the farnesyl diphosphate synthase gene (FDPS), BMD and bone turnover markers. METHODS: Two hundred and eighty-three community-dwelling Caucasian women aged 65 or older were screened from the greater Boston area. A validated FDPS SNP (rs2297480, A/C) was genotyped and evaluated for effect on bone mineral density (spine, hip,...
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