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Article

Computational simulation of interactions between SARS coronavirus spike mutants and host species-specific receptors.

Computational biology and chemistry - 1 Apr 2007

Zhang Yuan, Zheng Nan, Nan Peng, Cao Ying, Hasegawa Masami, Zhong Yang

Abstract excerpt

As a critical adaptive mechanism, amino acid replacements on the severe acute respiratory syndrome coronavirus (SARS-CoV) spike protein could alter the receptor-binding specificity of this envelope glycoprotein and in turn lead to the emergence or reemergence of this viral zoonosis. Based on the X-ray structures of SARS-CoV spike receptor-binding domain (RBD) in complex with its functional receptor...

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Source

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Identifiers

PMID: 17368104
DOI: 10.1016/j.compbiolchem.2007.02.006
PMCID: PMC7106403

Genes

ACE2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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