Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Introduction of a rod pigment aromatic cluster does not improve the structural stability of the human green cone pigment.

Journal of structural biology - 1 Aug 2007

Giesbers Maikel E, Bosman Giel J C G M, Bovee-Geurts Petra H M, DeGrip Willem J

Abstract excerpt

In the course of our studies on the structure/function relationship of visual pigments, we have expressed the human green cone pigment in the baculovirus/insect cell expression system. Purification of the human green cone pigment, however, has so far proven to be severely hampered by the low thermal stability of this receptor in a solubilized state. In order to overcome this problem, we tested a variety of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Glycerol
Share to Lipids
Share to Recombinant Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Retinal Cone Photoreceptor Cells

Share to Retinal Pigments

Share to Retinal Rod Photoreceptor Cells

Share to Sucrose

Share to Trehalose

Source

Identifiers

PMID: 17368048
DOI: 10.1016/j.jsb.2007.01.010

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Introduction of a rod pigment aromatic cluster does not improve the structural stability of the human green cone pigment.PMID 17368048Read ↗

Studies on the stability of the human cone visual pigments.Semantic proximity Read ↗

Pharmacological chaperone-mediated in vivo folding and stabilization of the P23H-opsin mutant associated with autosomal dominant retinitis pigmentosa.Semantic proximity Read ↗

Molecular basis for variations in the sensitivity of pathogenic rhodopsin variants to 9-cis-retinal.Semantic proximity Read ↗

A G Protein-Coupled Receptor Dimerization Interface in Human Cone Opsins.Semantic proximity Read ↗

Chromenone derivatives as novel pharmacological chaperones for retinitis pigmentosa-linked rod opsin mutantsSemantic proximity Read ↗

[Structural development study of a novel pharmacological chaperone for folding-defective rhodopsin mutants responsible for retinitis pigmentosa].Semantic proximity Read ↗

Mutation of a conserved cysteine in the X-linked cone opsins causes color vision deficiencies by disrupting protein folding and stability.Semantic proximity Read ↗

Retinobenzaldehydes as proper-trafficking inducers of folding-defective P23H rhodopsin mutant responsible for retinitis pigmentosa.Semantic proximity Read ↗

Retinoids assist the cellular folding of the autosomal dominant retinitis pigmentosa opsin mutant P23H.Semantic proximity Read ↗

Structural coupling of 11-cis-7-methyl-retinal and amino acids at the ligand binding pocket of rhodopsin.Semantic proximity Read ↗

Degradation of channelopsin-2 in the absence of retinal and degradation resistance in certain mutants.Semantic proximity Read ↗

Systematic profiling of temperature- and retinal-sensitive rhodopsin variants by deep mutational scanning.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.