Article
Molecular basis of β-thalassemia in the western province of Saudi Arabia: identification of rare β-thalassemia mutations.
Hemoglobin - 1 Jan 2011
Abuzenadah Adel M, Hussein Ibtessam M Ramzi, Damanhouri Ghazi A, A-Sayes Faten M, Gari Mamdouh A, Chaudhary Adeel G, Zaher Galila F, Al-Attas Asma'a, Al-Qahtani Mohammad H
Abstract excerpt
This study aimed at the identification of the spectrum of mutations in patients with β-thalassemia (β-thal) in the western province of Saudi Arabia. Screening for the mutations was done using the polymerase chain reaction-amplification refractory mutation system (PCR-ARMS) technique to test for 1...
Topics
- Adolescent
- Adult
- Alleles
- Base Sequence
- Child
- Child, Preschool
- DNA Mutational Analysis
- Female
- Gene Frequency
- Geography
- Humans
- Infant
- Male
- Mutagenesis, Insertional
- Mutation
- Point Mutation
- Polymerase Chain Reaction
- Saudi Arabia