Article
Molecular basis of β-thalassemia in the western province of Saudi Arabia: identification of rare β-thalassemia mutations.
Hemoglobin - 1 Jan 2011
Abuzenadah Adel M, Hussein Ibtessam M Ramzi, Damanhouri Ghazi A, A-Sayes Faten M, Gari Mamdouh A, Chaudhary Adeel G, Zaher Galila F, Al-Attas Asma'a, Al-Qahtani Mohammad H
Abstract excerpt
This study aimed at the identification of the spectrum of mutations in patients with β-thalassemia (β-thal) in the western province of Saudi Arabia. Screening for the mutations was done using the polymerase chain reaction-amplification refractory mutation system (PCR-ARMS) technique to test for 12 mutations, and direct automated DNA sequencing for the unknown samples. The study included 172 patients; of these 15...
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