Article
Gene expression profiling identifies FKBP39 as an inhibitor of autophagy in larval Drosophila fat body.
Cell death and differentiation - 1 Jun 2007
Juhász G, Puskás L G, Komonyi O, Erdi B, Maróy P, Neufeld T P, Sass M
Abstract excerpt
In Drosophila, the fat body undergoes a massive burst of autophagy at the end of larval development in preparation for the pupal transition. To identify genes involved in this process, we carried out a microarray analysis. We found that mRNA levels of the homologs of Atg8, the coat protein of early autophagic structures, and lysosomal hydrolases were upregulated, consistent with previous results. Genes encoding...
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