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Article

Structural framework for DNA translocation via the viral portal protein.

The EMBO journal - 4 Apr 2007

Lebedev Andrey A, Krause Margret H, Isidro Anabela L, Vagin Alexei A, Orlova Elena V, Turner Joanne, Dodson Eleanor J, Tavares Paulo, Antson Alfred A

Abstract excerpt

Tailed bacteriophages and herpesviruses load their capsids with DNA through a tunnel formed by the portal protein assembly. Here we describe the X-ray structure of the bacteriophage SPP1 portal protein in its isolated 13-subunit form and the pseudoatomic structure of a 12-subunit assembly. The first defines the DNA-interacting segments (tunnel loops) that pack tightly against each other forming the most...

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Source

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Identifiers

PMID: 17363899
DOI: 10.1038/sj.emboj.7601643
PMCID: PMC1847669

Genes

SPP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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