Article
Alterations in Expression of Glutamatergic Transporters and Receptors in Sporadic Alzheimer's Disease
1 Mar 2007
Abstract excerpt
Excitatory neurotransmitter dysfunction has been discussed to be involved in the pathophysiology of Alzheimer's disease (AD). In the current study we investigated gene and protein expression patterns of glutamatergic receptors and transporters in brains of AD patients in various stages of disease using gene chip arrays, real time PCR and immunohistochemistry. We found marked impairment in the expression of...
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