Article
Genetic and phenotypic characterization of drug-resistant Mycobacterium tuberculosis isolates in Hong Kong.
The Journal of antimicrobial chemotherapy - 1 May 2007
Chan Raphael C Y, Hui Mamie, Chan Edward W C, Au T K, Chin Miu L, Yip Chun K, AuYeang Carrie K W, Yeung Christina Y L, Kam Kai M, Yip Peter C W, Cheng Augustine F B
Abstract excerpt
OBJECTIVES: To characterize 250 drug-resistant Mycobacterium tuberculosis (MTB) isolates in Hong Kong with respect to their drug susceptibility phenotypes to five common anti-tuberculosis drugs (ofloxacin, rifampicin, ethambutol, isoniazid and pyrazinamide) and the relationship between such phenotypes and the patterns of genetic mutations in the corresponding resistance genes (gyrA, rpoB, embB, katG, inhA, ahpC...
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