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Article

Cerebellar GABAergic progenitors adopt an external granule cell-like phenotype in the absence of Ptf1a transcription factor expression.

Proceedings of the National Academy of Sciences of the United States of America - 20 Mar 2007

Pascual Marta, Abasolo Ibane, Mingorance-Le Meur Ana, Martínez Albert, Del Rio José A, Wright Christopher V E, Real Francisco X, Soriano Eduardo

Abstract excerpt

We report in this study that, in the cerebellum, the pancreatic transcription factor Ptf1a is required for the specific generation of Purkinje cells (PCs) and interneurons. Moreover, granule cell progenitors in the external GCL (EGL) appear to be unaffected by deletion of Ptf1a. Cell lineage anal...

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Identifiers

PMID: 17360405
DOI: 10.1073/pnas.0605699104
PMCID: PMC1829285

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17360405-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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