Article
Diabetic testicular dysfunction and spermatogenesis impairment: mechanisms and therapeutic prospects
25 Aug 2025
Abstract excerpt
With the global prevalence of diabetes mellitus (DM) steadily increasing, its impact on male reproductive health has become a growing area of concern. Diabetes-induced testicular damage involves alterations in testicular cell function, hormone levels, and the integrity of the blood-testis barrier (BTB), ultimately disrupting spermatogenesis. The key pathogenic factors include hyperglycemia, oxidative stress,...
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