Article
Transgenerational inheritance of susceptibility to diabetes-induced male subfertility.
Scientific reports - 10 Jul 2017
Pavlinkova Gabriela, Margaryan Hasmik, Zatecka Eva, Valaskova Eliska, Elzeinova Fatima, Kubatova Alena, Bohuslavova Romana, Peknicova Jana
Abstract excerpt
Male infertility is a worldwide problem associated with genetic background, environmental factors, and diseases. One of the suspected contributing factors to male infertility is diabetes mellitus. We investigated the molecular and morphological changes in sperms and testicular tissue of diabetic males. The study was performed in streptozotocin-induced type 1 diabetes mouse model. Diabetes decreased sperm...
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