Article
Phenotyping transgenic embryonic murine hearts using optical coherence tomography.
Applied optics - 1 Apr 2007
Jenkins Michael W, Patel Pankti, Deng Huayun, Montano Monica M, Watanabe Michiko, Rollins Andrew M
Abstract excerpt
We used optical coherence tomography (OCT) to characterize the morphological phenotype of embryonic murine hearts discerning hexamethylene-bis-acetamide-inducible protein 1 (HEXIM1) mutants from their wild-type littermates. At E12.5 and E13.5 murine embryos were excised from the mother, the hearts were removed, and 3D OCT data sets were obtained from each heart in the litter. Next, we segmented the morphological...
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