Article
[The association of methylenetetrahydrofolate reductase gene polymorphism with nephropathy in type 2 diabetes mellitus in Chinese].
Zhonghua nei ke za zhi - 1 Aug 2001
Sun J, Xu Y, Zhu Y
Abstract excerpt
OBJECTIVE: To evaluate the role of methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms in Chinese patients with type 2 diabetes mellitus and diabetic nephropathy(DN). METHODS: 85 type 2 diabetes mellitus patients and 57 controls were recruited in the study. MTHFR genetic C677T polymorphism was determined with PCR-restriction fragment length polymorphisms (RFLP). Plasma total homocysteine level was...
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