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Article

No association between the common MTHFR 677C->T polymorphism and venous thrombosis: results from the MEGA study.

Archives of internal medicine - 12 Mar 2007

Bezemer Irene D, Doggen Carine J M, Vos Hans L, Rosendaal Frits R

Abstract excerpt

BACKGROUND: Increased homocysteine levels are related to the occurrence of venous thrombosis, but whether this relation is causal is unclear. The T-variant of the common methylenetetrahydrofolate reductase (MTHFR) 677C-->T polymorphism mildly increases homocysteine levels. Meta-analyses have demonstrated a weak effect of the MTHFR 677TT genotype on risk but are sensitive to selective publication of positive...

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Identifiers

PMID: 17353498
DOI: 10.1001/archinte.167.5.497

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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No association between the common MTHFR 677C->T polymorphism and venous thrombosis: results from the MEGA study.PMID 17353498Read ↗

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