Article
Lack of association between the C677T mutation in the 5,10-methylenetetrahydrofolate reductase gene and venous thromboembolism in Northwestern Greece.
International angiology : a journal of the International Union of Angiology - 1 Sept 2002
Zalavras Ch G, Giotopoulou S, Dokou E, Mitsis M, Ioannou H V, Tzolou A, Kolaitis N, Vartholomatos G
Abstract excerpt
BACKGROUND: Hyperhomocysteinemia has been associated with venous thrombosis. Under known and unknown conditions the C677T mutation in the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene is accompanied by elevated levels of homocysteine. However, the relationship of this mutation with venous thromboembolism (VTE) remains controversial. The purpose of this study was to evaluate the association of the MTHFR...
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