Article
Nationwide study of clinical and molecular features of hereditary non-polyposis colorectal cancer (HNPCC) in Latvia.
Anticancer research - 1 Jan 2000
Irmejs Arvids, Borosenko Viktors, Melbarde-Gorkusa Inga, Gardovskis Andris, Bitina Marianna, Kurzawski Grzegorz, Suchy Janina, Gorski Bohdan, Gardovskis Janis
Abstract excerpt
BACKGROUND: The mutational spectrum of mismatch repair (MMR) genes in the Baltic States has been reported to be quite similar to that in Poland; however during a country-wide study considerable differences in the population of Latvia were discovered. This study was undertaken to investigate the clinical and molecular features of HNPCC in Latvia. MATERIALS AND METHODS: Family cancer histories were collected, from...
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