Article
Anxiety and comorbid measures associated with PLXNA2.
Archives of general psychiatry - 1 Mar 2007
Wray Naomi R, James Michael R, Mah Steven P, Nelson Matthew, Andrews Gavin, Sullivan Patrick F, Montgomery Grant W, Birley Andrew J, Braun Andreas, Martin Nicholas G
Abstract excerpt
CONTEXT: Reduction in adult neurogenesis has been proposed as a mechanism for onset of depression. Semaphorins and their coreceptors, plexins, have been implicated in nervous system development and in adult neurogenesis. A recent genomewide association study of schizophrenia identified a variant of the gene encoding plexin A2 (PLXNA2) to be most consistently associated across study samples. Common genetic...
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