Article
Modeling protein-protein complexes involved in the cytochrome C oxidase copper-delivery pathway.
Journal of proteome research - 1 Apr 2007
van Dijk Aalt D J, Ciofi-Baffoni Simone, Banci Lucia, Bertini Ivano, Boelens Rolf, Bonvin Alexandre M J J
Abstract excerpt
Proper assembly and function of cytochrome c oxidase, which catalyzes the reduction of O2 and generates the proton gradient driving ATP synthesis, depend on correct copper delivery and incorporation. Structural details about the protein-protein complexes involved in this process are still missing. We describe here models of four complexes along this pathway obtained by combining bioinformatics interface...
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