Article
The axon guidance gene lola is required for programmed cell death in the Drosophila ovary.
Developmental biology - 15 Apr 2007
Bass B Paige, Cullen Kristen, McCall Kimberly
Abstract excerpt
longitudinals-lacking (lola) was identified in Drosophila as a gene encoding several alternatively spliced transcription factors involved in axon guidance. Here we report that lola also plays a critical role in programmed cell death in the ovary. lola mutant germline clones show a high percentage of egg chambers with nurse cell nuclei persisting past stage 13, indicating a block in developmental nurse cell death....
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