Article
lola encodes a putative transcription factor required for axon growth and guidance in Drosophila.
Development (Cambridge, England) - 1 Jun 1994
Giniger E, Tietje K, Jan L Y, Jan Y N
Abstract excerpt
Mutations in the gene longitudinals lacking (lola) lead to defects in the development of axon tracts in the Drosophila embryonic central nervous system. We now show that lola mutations also cause defects of axon growth and guidance in the peripheral nervous system, and causes a particular cluster...
Topics
- Amino Acid Sequence
- Animals
- Axons
- Base Sequence
- Central Nervous System
- Drosophila
- Genes, Insect
- Immunohistochemistry
- Molecular Sequence Data
- Mutation
- Peripheral Nervous System
- Phenotype
- Transcription Factors