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Article

The human POLH gene is not mutated, and is expressed in a cohort of patients with basal or squamous cell carcinoma of the skin.

International journal of molecular medicine - 1 Apr 2007

Flanagan Annabelle M, Rafferty Gerard, O'Neill Anne, Rynne Leonie, Kelly Jack, McCann Jack, Carty Michael P

Abstract excerpt

Skin cancer, the most common cancer in the general population, is strongly associated with exposure to the ultraviolet component of sunlight. To investigate the relationship between DNA damage processing and skin tumour development, we determined the POLH status of a cohort of skin cancer patients. The human POLH gene encodes DNA polymerase eta (poleta), which normally carries out accurate translesion synthesis...

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Source

Identifiers

PMID: 17334634

Genes

POLH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The human POLH gene is not mutated, and is expressed in a cohort of patients with basal or squamous cell carcinoma of the skin.PMID 17334634Read ↗

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Overproduction of DNA polymerase eta does not raise the spontaneous mutation rate in diploid human fibroblasts.Semantic proximity Read ↗

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