Article
Meta-analysis in genome-wide association datasets: strategies and application in Parkinson disease.
PloS one - 7 Feb 2007
Evangelou Evangelos, Maraganore Demetrius M, Ioannidis John P A
Abstract excerpt
BACKGROUND: Genome-wide association studies hold substantial promise for identifying common genetic variants that regulate susceptibility to complex diseases. However, for the detection of small genetic effects, single studies may be underpowered. Power may be improved by combining genome-wide da...
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