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Article

Genetic and acquired inflammatory conditions are synergistically associated with early carotid atherosclerosis.

Stroke - 1 Sept 2006

Markus Hugh S, Labrum Robyn, Bevan Steve, Reindl Markus, Egger Georg, Wiedermann Christian J, Xu Qingbo, Kiechl Stefan, Willeit Johann

Abstract excerpt

BACKGROUND AND PURPOSE: If chronic inflammation plays a causal role in atherogenesis, individuals with proinflammatory gene variants would be expected to develop more atherosclerosis. We recently found a synergistic association between 3 functional proinflammatory gene polymorphisms/haplotypes and smoking on carotid intima-media thickness (IMT). We replicated this finding in a second large population and extended...

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Source

Identifiers

PMID: 16873708
DOI: 10.1161/01.STR.0000236637.72124.3f

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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